Morbidity: China: ethmoid frontal sphenoid maxillary Abroad frontal ethmoid sphenoid maxillary Symptoms sign: Orbital apex syndrome Facial protrude Rhinorrhea, nasal obstruction, hyposmia Diagnosis: History, symptoms and sign Punction. X-ray/CT scan TTreatment. Operation: open surgery, marsupializationMorbidity: China: ethmoid > frontal > sphenoid > maxillary Abroad: frontal > ethmoid > sphenoid > maxillary Symptoms & Sign： Orbital apex syndrome Facial protrude Rhinorrhea, nasal obstruction, hyposmia Diagnosis: History, symptoms and sign Punction, X-ray/CT scan Treatment: Operation: “open surgery”, marsupialization