nonagE mediated, T lymphocyte dependent pathway In delayed type allergic reaction, Th2 cell directly initiates imflammatory response by activation and agglutination of various inflammatory cells via the release of multiple cytokines(IL-4、I-13、I-3 IL-5)nonIgE mediated, T lymphocyte dependent pathway • In delayed type allergic reaction, Th2 cell directly initiates imflammatory response by activation and agglutination of various inflammatory cells via the release of multiple cytokines(IL-4、IL-13、IL-3、 IL-5）