Why does cic deposit in the glomeruli? Large area of glomerular capillaries more chances to contact Net structure of cic easy to deposit and settle down Clearance dysfunction of mesangial cells disability of mononuclear macrophage, component or function defect of complements Decrease clearance of cicWhy does CIC deposit in the glomeruli? • Large area of glomerrular capillaries --more chances to contact • Net structure of CIC --easy to deposit and settle down • Clearance dysfunction of mesangial cells, disability of mononuclear macrophage, component or function defect of complements Decrease clearance of CIC