Physical Methods of Microbial Control Filtration removes microbes Low temperature inhibits microbial growth ·Refrigeration ·Deep freezing ·Lyophilization High pressure denatures proteins Desiccation prevents metabolism Osmotic pressure causes plasmolysis• Filtration removes microbes • Low temperature inhibits microbial growth • Refrigeration • Deep freezing • Lyophilization • High pressure denatures proteins • Desiccation prevents metabolism • Osmotic pressure causes plasmolysis Physical Methods of Microbial Control