Regulatory interactions not included in iMH805/775 that participate in 15 or more regulatory cascades identified by the network expansion approach Promoter Number of occupant emulator Target cascades score Motif Involving only metabolic TEs Hap2/ Hap4 GCN4 95 Gcn4 LEU3 70 4.51 Hapl MOT3 46 7.21 GIn 3 GCN4 32 5.82 Gcn4 GLN3 24 3.49 HAP4 19 2.17 YYYYYYY GIn 3 HAPT 16 2.26 Leu3 TYEZ 16 2.52 Rox1 HAPT 16 2.25 Involving other tfs Cup YAP 53 4.29 Gcn ABF1 46 2.04 Yap CINS 31 3.6 Leu3 TEC1 21 2.42 Gat1 CUP 19 2.21 Leu3 MSN4 19 2.33 Tye7 MSN2 18 603 NYYYYYYYY Hap4 /Hap5 DIG 295 Yap GCN4 16 2.51Regulatory interactions not included in iMH805/775 that participate in 15 or more regulatory cascades identified by the network expansion approach