Bacteria induce macrophages to produce IL-6, which acts on hepatocytes to induce synthesis of acute-phase proteins SP-D manal binding actin C-reaceve anmmy'od prolein protein serum C-reactive protein binds phosphorylcholine Mannan-binding lectin binds mannose on bacterial surfaces, acting as an residues on bacterial surfaces, acting as an opsonin, and also activating complement opsonin, and also activating complement