Medical Genetics In 1904 the doctor Archibald E. garrod described alkaptonuria a disease he classified as a lifelong congenital chemical alteration Later on in 1909 he described other diseases albinism cystinuria porphyria and pentosuria which he named inborn Errors of metabolism", Garrod 's conclusions were completely correct in relation to the genetic basis of metabolic disorders and the gene-enzyme conceptMedical Genetics In 1904 the doctor Archibald E. Garrod described alkaptonuria, a disease he classified as a lifelong congenital chemical alteration. Later on, in 1909, he described other diseases: albinism, cystinuria, porphyria and pentosuria, which he named "Inborn Errors of Metabolism". Garrod's conclusions were completely correct in relation to the genetic basis of metabolic disorders and the gene-enzyme concept