Immunocompromised Host Individual who has one or more defects in the body's natural defense mechanisms which are sufficiently severe to predispose the host to life threatening infection Primary -PID, damage to anatomical barriers Secondary -infection, tumor, drug, others Physiology- Infants, aged Wang Xiaochuan Children's HospitalWang Xiaochuan Children’s Hospital Immunocompromised Host • Individual who has one or more defects in the body’s natural defense mechanisms which are sufficiently severe to predispose the host to life￾threatening infection • Primary - PID, damage to anatomical barriers • Secondary - infection, tumor, drug, others • Physiology- Infants, aged