Laboratory studies 2. Bone age 3. Head mri or ct 4. IGF-1 and igfbp-3 levels Low values of igf-i and igfbp-3 suggest GHD 5. Other pituitary hormones 6. Karyotype2. Bone age 3. Head MRI or CT 4. IGF-1 and IGFBP-3 levels – Low values of IGF-1 and IGFBP-3 suggest GHD 5. Other pituitary hormones 6. Karyotype Laboratory Studies