and platelets,enhanced phagocytosis,chemotaxis of phagocytes,and activation of lymphocytes and macrophages. Biological Activities Promoted by C5a Comtraction of Releaseo a品 The main activity of C3a and C5a is anaphylaxis.These cause histamine release from mast cells and basophils,which can affect the activity of smooth muscle. Spasmogenicity,accounts for the ability of these molecules to induce an anaphylactic response in animals.In addition to spasmogenicity,histamine release induced by the anaphylatoxins as effects on inflammation. The cellular responses of neutrophils and monocytes to C5a include (1)degranulation and lysosomal enzyme release,(2)cell adherence,and (3)chemotactic migration. Events of Inflamation Mediated by Complement Products C3% INFLAMMATION permebaee) The acute inflammatory response is characterized by symptoms of redness,pain, swelling,and heat due to the action of C4a,C3a,C5a,and histamine.Inflammation's primary goal is to set into motion a series of events that result in the elimination of foreign and damaged cells. This response can be mediated by the anaphylatoxins and their byproducts.and platelets, enhanced phagocytosis, chemotaxis of phagocytes, and activation of lymphocytes and macrophages. The main activity of C3a and C5a is anaphylaxis. These cause histamine release from mast cells and basophils, which can affect the activity of smooth muscle. Spasmogenicity, accounts for the ability of these molecules to induce an anaphylactic response in animals. In addition to spasmogenicity, histamine release induced by the anaphylatoxins as effects on inflammation. The cellular responses of neutrophils and monocytes to C5a include (1) degranulation and lysosomal enzyme release, (2) cell adherence, and (3) chemotactic migration. The acute inflammatory response is characterized by symptoms of redness, pain, swelling, and heat due to the action of C4a, C3a, C5a, and histamine. Inflammation's primary goal is to set into motion a series of events that result in the elimination of foreign and damaged cells. This response can be mediated by the anaphylatoxins and their byproducts