BEH.462/3. 962J Molecular Principles of Biomaterials Spring 2003 o 250 g1600 9d2日0:0d 20o1/2/3 1200 150 900 md 1234567日101112 pH of Swelling Medium 5678101112 pH of Swelling Medium Fig. 3. Theoretical swelling predictions at comparable ionic strength conditions for an anionic network with Fig 4. Theoretical swelling predictions at comparable ionic (1)pKn=202)pK。=40(3)pKn=60.(4pkn=80.andstrengthcondtionstrananionienetworkwith(r=005 pKa=10.0 (2)I=0.1,(3)I=0.25,(4)I=0.5,(5)I=0.75,(6)I=10, and(7)I=20. References 1. James, H M.& Guth, E Simple presentation of network theory of rubber, with a discussion of other theories. J. Poym.Sc.4,153-182(1949) Flory, P J. Rehner Jr, J. Statistical mechanics of cross-linked polymer networks. L. Rubberlike elasticity. J. chem.Phys.11,512-520(1943) 3. Flory, P J& Rehner Jr, J. Statistical mechanics of cross-linked polymer networks. IL Swelling. J. Chem. Phys 11,521-526(1943 Brannonpeppas, L& Peppas, N. A Equilibrium Swelling Behavior of Ph-Sensitive Hydrogels. Chemical Engineering: pvatpololyvinyl-Alcohol)Hydrogels-Reinforcement of Radiation-Crosslinked Networks 715-722(1991) N.A. by Crystallization. Journal of Polymer Science Part a-Polymer Chemistry 14, 441-457(1976) Ozyurek, C, Caykara, T, Kantoglu, O& Guven, O. Characterization of network structure of poly(N-vinyl 2- pyrrolidone/acrylic acid) polyelectrolyte hydrogels by swelling measurements. Journal of Polymer Science Part B Polymer PhysicS 38, 3309-3317(2000) Lecture 9-polyelectrolyte hydrogels 6 of 6BEH.462/3.962J Molecular Principles of Biomaterials Spring 2003 References 1. James, H. M. & Guth, E. Simple presentation of network theory of rubber, with a discussion of other theories. J. Polym. Sci. 4, 153-182 (1949). 2. Flory, P. J. & Rehner Jr., J. Statistical mechanics of cross-linked polymer networks. I. Rubberlike elasticity. J. Chem. Phys. 11, 512-520 (1943). 3. Flory, P. J. & Rehner Jr., J. Statistical mechanics of cross-linked polymer networks. II. Swelling. J. Chem. Phys. 11, 521-526 (1943). 4. Brannonpeppas, L. & Peppas, N. A. Equilibrium Swelling Behavior of Ph-Sensitive Hydrogels. Chemical Engineering Science 46, 715-722 (1991). 5. Peppas, N. A. & Merrill, E. W. Polyvinyl-Alcohol) Hydrogels - Reinforcement of Radiation-Crosslinked Networks by Crystallization. Journal of Polymer Science Part a-Polymer Chemistry 14, 441-457 (1976). 6. Ozyurek, C., Caykara, T., Kantoglu, O. & Guven, O. Characterization of network structure of poly(N-vinyl 2- pyrrolidone/acrylic acid) polyelectrolyte hydrogels by swelling measurements. Journal of Polymer Science Part B￾Polymer Physics 38, 3309-3317 (2000). Lecture 9 – polyelectrolyte hydrogels 6 of 6