Nucleophilicity(亲核性) CH3CO2<CI-<Br N3<CH3O<CN- <I<SCN-<CH2S- ■Parallels basicity H20<C2H302<OH Increases down the periodic table I>CI->F- Anions are more nucleophilic than neutral compounds ■The solvent matters!College Nucleophilicity(亲核性 of Science ) CH 3CO 2 - < Cl - < Br - < N 3 - < CH 3 O - < CN - < I - < SCN - < CH 3 S - Parallels basicity – H 2O < C 2 H 3 O 2 - < OH - Increases down the periodic table – I - > Cl - > F - Anions are more nucleophilic than neutral compounds The solvent matters!