rapidly through the column and emerge irs 1. 2. 2 Larger protein molecules flow mor because the ley cannot enter the internal volume of the beads 1.2.3 Proteins smaller than the diameter of the pores on the beads will enter the labyrinthian path of the beads and hence, are slowed in mobility(Manufacturer controls the properties such as pore size distribution, of the beads.) 1.2.4 Gel-filtration usually has low resolution1.2.2 Larger protein molecules flow more rapidly through the column and emerge first because they cannot enter the internal volume of the beads. 1.2.3 Proteins smaller than the diameter of the pores on the beads will enter the labyrinthian path of the beads, and hence, are slowed in mobility. (Manufacturer controls the properties, such as pore size distribution, of the beads.) 1.2.4 Gel-filtration usually has low resolution