ver: periport 4. Brain cortical/subcortical areas 5. Heart: increase of cardiac afterload, prelod may or v 6. Hematological changes: hypercoagulation status, HELLP(hemolysis, elevated liver enzymes, low count platelets) Clinical finding. Proteinuria is a very common finding in preeclampsia (1) Hypertension is the most significant primary sign of PIHs (3) Edema is a common first sign of impending or actual preeclampsia classified into 4 degrees Degree 1: edema involves in shanks 2: edema involve in thighs 3. edema involves in vulva and abdomen 4: edema involves face and fingers (4) Headache (5) Visual disturbances (6) The tightness of chest (7) Convulsion3. Liver : periportal areas 4. Brain :cortical /subcortical areas 5. Heart :increase of cardiac afterload , prelod may  or . 6. Hematological changes: hypercoagulation status, HELLP(hemolysis, elevated liver enzymes,low count platelets) Clinical finding : (1) Hypertension is the most significant primary sign of PIHs. (2) Proteinuria is a very common finding in preeclampsia (3) Edema is a common first sign of impending or actual preeclampsia . classified into 4 degrees : Degree 1 : edema involves in shanks 2 : edema involve in thighs 3 : edema involves in vulva and abdomen 4 : edema involves face and fingers (4) Headache (5) Visual disturbances (6) The tightness of chest (7) Convulsion