AUG GCC TGc AAA CGC TGG normal met ala cys lys arg trp Single nucleotide polymorphisms (SNP)are the most common type genetic variation. A SNP is AUG GCT TGC AAA CGC TGG silent single base pair mutation at a met ala cys lys arg trp specific locus SNPs are often found to be the etiology of many human diseases and are AUG GCC TGA AAA CGC TGG becoming of particular interest in nonsense met ala pharmacogenetics AUG GCC GGC AAA CGC TGG missense met ala arg lys arg trp AUG GC. TGC AAA CGC TGG frameshift (deletion-1) met ala glu asn ala AUG GCC C TGC CGC TGG frameshift insertion +1) met ala leu ghn thrleu insertion +1, AUG GCC C TGC AAA -GC TGG met ala leu gIn thr pSingle nucleotide polymorphisms (SNP) are the most common type of genetic variation. A SNP is a single base pair mutation at a specific locus. SNPs are often found to be the etiology of many human diseases and are becoming of particular interest in pharmacogenetics