Regulator T Cells带 Second, inositol triphosphate causes Ca channel to open; Ca++ ions rush in cytosol; activation of calmodulin calcineurin, and nuclear factor of activated tu1 BIOL 533 18 Lecture 7BIOL 533 18 Lecture 7 Regulator T Cells – Second, inositol triphosphate causes Ca channel to open; Ca++ ions rush in cytosol; activation of calmodulin, calcineurin, and nuclear factor of activated TH1