cell,2002,14:1605-1619 [7 Mette M F, Winden J, Matzke M, et al. Short RNAs Can Identify New Candidate Transposable Element Families in Arabidopsis Plant Physiol, 2002, 130: 6-9 [8] Park W, Li JJ, SongR, et al. CARPEL FACTORY, a Dicer Homolog and HENI a Novel Protein, Act microRNA Metabolism in Arabidopsis thaliana. Curr Biol 2002, 12: 1484-1495 9] Reinhart B J, Weinstein E G, Rhoades M W,et al. MicroRNAs in plants. Genes Dev 2002, 16: 1616-1626 [10 Griffit hs Jones S, Grocock R, van Dongen S, et al. miRBase: microRNA sequences, targets and gene menclature[J]. Nucleic Acids Res, 2006, 34 ( Database issue): D1402D14 [11 Baulcombe D DNA events: an RNa microcosm. Science, 2002, 297(5589): 2002-2003 [12] Gary R Glimp se of a tiny RNA world. Science, 2001, 294: 797-799. [13] Lee RC, Ambros v An extensive class of small RNAs in Caenorhabditis elegans Science,2001,294:862-864 [14]Reinhart B J, Weinstein EG, Rhoades M w, Bartel B, Bartel D P. MicroRNAs in plants]. Genes Deva 2002,!6(13):1616-1626 [15]Chen X M. microrNa biogenesis and function in plants J].FEBS Lett, 2005, 579(8): 5923-5931 [16]Reinhart B J, Weinstein E G, Rhoades M WMicroRNAs in plants[].Genes Dev. 2002, 16(13): 1616-1626 [ 17]Barrel B, Barrel D P MicroRNAs: at the root of plant development!] Plant Physiol, 2003, 132(2): 709-717 [18]Tan gGL, Reinhart B J, Barrel D P, Zamore P D, A biochemical framework for RNA silencing in plants I JI Genes Dev, 2003, 17(1): 49-6 [1]江舸,金由辛.微RNA- Science杂志2002年十大科技突破第一名.生命的化学,2003,23:1-3 20 Millar AA, Waterhouse PM. Plant and animal microRNAs: similarities and differences. Funct Integr Genomics,2005,5:129-135 []Chang S, JohnstonR J, Frokjoer-jensen C, et al. MicroRNAs act sequentially and asymmetrically to control hemosensory laterality in the nematode. Nature, 2004, 430: 785-789 [2龙茹李玉花徐启江动植物mRNA的生物合成、作用机理及其功能.生命科学,2007(19)2:127-131 23Wightman B, Ha l, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans Cell, 1993, 75: 855-86 [24] Moss E G, Lee r c, ambros V The cold shock domain protein LIN-28 controls developmental Celegans and is regulated by the lin-4 RNA Cell, 1997, 88: 637-646 [25JYekta, S, Shih, IH, and Bartel, D P. MicroRNA-directed cleavage of HOXB8 m RNA. Science, 2004, 304:594-596 26]Schwab R, Palatnik J F, Riester M, et al. Specific effects of microRNAs on the plant transcriptome. Dev Cell, 2005,8:517-527 27 Lin SYet al. The C. elegans hunchback Homolog, hbl-1, Controls Temporal Patterning and Is a Probable MicroRNA Target. Dev Cell. 2003. 4: 639-650Cell ,2002 ,14 :1605-1619 [7]Mette M F ,Winden J ,Matzke M,et al. Short RNAs Can Identify New Candidate Transposable Element Families in Arabidopsis. Plant Physiol ,2002 ,130 :6-9 [8]Park W,Li J J ,Song R ,et al. CARPEL FACTORY,a Dicer Homolog ,and HEN1 ,a Novel Protein ,Act in microRNA Metabolism in Arabidopsis thaliana. Curr Biol ,2002 ,12 :1484-1495 [9]Reinhart B J ,Weinstein E G,Rhoades M W,et al.MicroRNAs in plants. Genes Dev ,2002 ,16 :1616-1626 [10] Griffit hs Jones S , Grocock RJ , van Dongen S , et al . miRBase : microRNA sequences , targets and gene nomenclature[J ] . Nucleic Acids Res , 2006 , 34 (Database issue) : D1402D144. [11]Baulcombe D. DNA events : an RNA microcosm. Science , 2002 ,297 (5589) : 2002-2003 [12]Gary R. Glimp se of a tiny RNA world. Science, 2001, 294: 797-799. [13] Lee RC ,Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science ,2001 ,294 :862-864 [14]Reinhart B J，Weinstein E G，Rhoades M W ，Bartel B，Bartel D P． MicroRNAs in plants[J]．Genes Dev。 2002,l6(13):1616-1626 [15]Chen X M．microRNA biogenesis and function in plants[J].FEBS Lett,2005,579(8):5923-5931 [16]Reinhart B J,Weinstein E G,Rhoades M W.MicroRNAs in plants[J].Genes Dev.2002,l6(13):1616-1626 [17]Barrel B,Barrel D P.MicroRNAs:at the root of plant development[J] Plant Physiol,2003,132(2):709-717 [18]Tan g G L,Reinhart B J,Barrel D P,Zamore P D,A biochemical framework for RNA silencing in plants l J],Genes Dev,2003,l7(1):49-63 [19] 江 舸, 金由辛. 微RNA-Science 杂志 2002 年十大科技突破第一名. 生命的化学, 2003, 23: 1-3 [20] Millar A A, Waterhouse P M. Plant and animal microRNAs: similarities and differences. Funct Integr Genomics, 2005, 5:129-135 [21]Chang S, Johnston R J, Frøkjoer-jensen C, et al. MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode. Nature, 2004, 430: 785-789 [22]龙 茹,李玉花,徐启江.动植物miRNA 的生物合成、作用机理及其功能. 生命科学,2007（19)2:127-131 [23] Wightman B, Ha I, Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell, 1993, 75: 855-862 [24] Moss E G, Lee R C, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C.elegans and is regulated by the lin-4 RNA. Cell, 1997, 88: 637-646 [25]Yekta, S, Shih, I.H, and Bartel, D.P.MicroRNA-directed cleavage of HOXB8 mRNA. Science,2004, 304: 594-596 [26] Schwab R, Palatnik J F, Riester M, et al.. Specific effects of microRNAs on the plant transcriptome. Dev Cell, 2005, 8: 517-527. [27] Lin SY et al. The C. elegans hunchback Homolog, hbl-1,Controls Temporal Patterning and Is a Probable MicroRNA Target.Dev Cell, 2003, 4: 639-650