17.Introduction Amplification refers to the production of additional copies of a chromosomal sequence, found as intrachromosomal or extrachromosomal dNa Transgenic animals are created by introducing new DNA sequences into the germline via addition to the egg 消当Amplification refers to the production of additional copies of a chromosomal sequence, found as intrachromosomal or extrachromosomal DNA. Transgenic animals are created by introducing new DNA sequences into the germline via addition to the egg. 17.1 Introduction