Donor DNA Endonuclease nicks DNA Molecular mechanism of genetic recombination Nick 0 Binding of SSB protein SSB protein Processes: 00000 Recipient DNA 1.Nick formation Strand RecA invasion 2.Strand invasion protein 000 3.Heteroduplex formation 源双链核酸的形成 Development of cross-strand exchange 4.Resolution of heteroduplex complex (SSB)single-stranded binding protein Resolution Resolution at sites at Vsites Patches Splices 2012 Pearson Education,Inc.Molecular mechanism of genetic recombination Processes: 1. Nick formation 2. Strand invasion 3. Heteroduplex formation异 源双链核酸的形成 4. Resolution of heteroduplex complex (SSB) single-stranded binding protein