3. The acetyl and malony groups are first transferred to two-SH groups of the fatty acid synthase complex o The acetyl group of acetyl-Coa is first transferred to the-sh group of a Cys residue on the B-ketoacyl ACP synthase(Ks)in a reaction catalyzed by acetyl-CoA-ACP transacetylase(AT) o The malonyl group is transferred from malonyl-COA to the-SH group of the 4 -phosphopantetheine covalently attached to a Ser residue of the acyl carrier protein(ACP)3. The acetyl and malony groups are first transferred to two –SH groups of the fatty acid synthase complex ⚫ The acetyl group of acetyl-CoA is first transferred to the –SH group of a Cys residue on the b-ketoacyl￾ACP synthase (KS) in a reaction catalyzed by acetyl-CoA-ACP transacetylase (AT). ⚫ The malonyl group is transferred from malonyl-CoA to the –SH group of the 4`-phosphopantetheine covalently attached to a Ser residue of the acyl carrier protein (ACP)