(4) Enzyme components PHospholipase(PL): PLA2, C, D, SMase(sphingomyelinase) @Phosphatidylinositol kinase: PI-3K, P1-4K, PI-SK/PTEN 3GP (Tripolymer& Small ) GP(Ga)=GTPase @Protein kinase& phosphatase: PSTK& TPK or PTK 5AC, GC/ cyclic nucleotide phosphodiesterase phosphatase and tensin homolog deleted on chromosome ten(PTEn)(4) Enzyme components ①Phospholipase(PL) : PLA2 , C, D, SMase (sphingomyelinase) ②Phosphatidylinositol kinase: PI-3K, PI-4K, PI-5K / PTEN ③GP (Tripolymer & Small ) : GP(G) = GTPase ④Protein kinase & phosphatase: PSTK & TPK or PTK ⑤AC, GC/ cyclic nucleotide phosphodiesterase: phosphatase and tensin homolog deleted on chromosome ten (PTEN)