Yang et al.BMC Complementary and Alternative Medicine (2015)15:93 Page 4 of 8 Enrollment Six Institutions Stratified sampling Three VA Homes(n=156) Three LTC Facilities(n=120) Randomized Allocation A0ma8yr件gp0=82) VA Homein=50) Aroma-group=10的 Control-group(n=88) VAHomen=50) LTC facilit=2)) VA Homen=5的 LTC facility(n=50) LTC facility (n=38) Excluded(n=26) Excluded.(n=33) Excluded-(n=31) ◆-Declinedto ◆D1ind1c participa a=25 ◆0比150时 ◆0t壮英0 ◆0hg0n3 a=5) 红=8 位=3 Aroma-acupressur行p Aroma-group Control-group Acdt0i世ro=50 Allocated tointervention/n=73) A1 located toim320r=5刀 ◆Received allocated interventio如 ◆Received allocatedintervention在=3y) ◆R.d-allocated interventi0n在=57) 红=56-) Follow-Up Follow-up(a=5句 Follow-up(n=73y Follow-up(n=57) Analysis Analyied CMAIdata(n=56) Analysed CMAIdatan=73) Analyzed C1AId0=3) Ad-B.Vda红=0),complete Arad-HB.Vdata红=61),complete Anad-HB.V data红=49y, io:89296 0.83.696 completeratio:8696 ◆Excluded fom HRVanalvais(n=-. .Excluded fom HRV-analysis(n=12)Due ◆Excluded fom HR.V知ya=8) Due to participants'un-cooperation. to participanta'un-cooperation. Dt0 participant'出-80pza0 Figure 1 Participant flow in the study following the interventions.After further comparison of the According to the HRV,the LF/HF was significantly declining CMAl scores between the aroma-acupressure higher compared with the control group only in the aroma- and aromatherapy groups in the post-test and post- acupressure group;each measurement in the aroma- three-week assessments,the decline in the aroma-acupressure group was significantly higher compared with acupressure group was larger compared with that in the the control group.The result is generally consistent with aromatherapy group,which demonstrates that aroma- previous acupuncture study,which showed the sympathetic acupressure was better able to improve agitation com- nervous system activity in the aroma-acupressure group pared with aromatherapy. was stronger compared with the control group [19];thisfollowing the interventions. After further comparison of the declining CMAI scores between the aroma-acupressure and aromatherapy groups in the post-test and postthree-week assessments, the decline in the aromaacupressure group was larger compared with that in the aromatherapy group, which demonstrates that aromaacupressure was better able to improve agitation compared with aromatherapy. According to the HRV, the LF/HF was significantly higher compared with the control group only in the aromaacupressure group; each measurement in the aromaacupressure group was significantly higher compared with the control group. The result is generally consistent with previous acupuncture study, which showed the sympathetic nervous system activity in the aroma-acupressure group was stronger compared with the control group [19]; this Figure 1 Participant flow in the study. Yang et al. BMC Complementary and Alternative Medicine (2015) 15:93 Page 4 of 8