国生earning Objectives of Tablets 生earning Objectives of Tablets TabletexcDiluents (fillers),Moistening Ingredients properties which affect the mixing Evalution:Appearance,Weight variation,Hardness agents and adhesives,Disintegrarts,Lubricants Mechanism of wet granulation and Friahility,Disintegration test,Content (Lubricant,Antiadheren,Glidant),Absorbents, Instruments for granulation uniformity.Dissoluton test Coloring agents,Flavoring agents... Mechanism of Disintegrants Dry bulb temperature,Wet bulb temperature, Methods of preparation:Wet granulation,Dry granulation,Direct compression,characteristics and hhe procedure Advantages and disadvantages of wet granulation Advantages of Crushing Learning Objectives of Tablets Coating:Sugar coting film coating,compression coating Aqueous polymeric dispersions Polymer,Plasticer Pore material,Pigment,Antiadherent Film formation mechanism of aqucous polymeri dispersions Coating methods:Pan coating,Roll coating Fluidized bed cooting,Compr 2020 Shanghai Jiao Tong University Learning Objectives of Tablets Tablet excipients: Diluents (fillers), Moistening agents and adhesives, Disintegrants, Lubricants (Lubricant, Antiadherent, Glidant), Absorbents, Coloring agents, Flavoring agents… Mechanism of Disintegrants Methods of preparation: Wet granulation, Dry granulation, Direct compression, characteristics and procedure Advantages of Crushing Shanghai Jiao Tong University Learning Objectives of Tablets Ingredients properties which affect the mixing Mechanism of wet granulation Instruments for granulation Dry bulb temperature, Wet bulb temperature, Relative humidity, Equilibrium water, Free water, Bound water, Nonbound water Advantages and disadvantages of wet granulation Shanghai Jiao Tong University Learning Objectives of Tablets Evaluation: Appearance, Weight variation, Hardness and Friability, Disintegration test, Content uniformity, Dissolution test Factors affecting tablet formation: Properties of drug and excipients (Plasticity and elasticity, Melting point, Crystalline), Pressure, Moisture, Binders, Lubricants Shanghai Jiao Tong University Learning Objectives of Tablets Coating: Sugar coating, film coating, compression coating Aqueous polymeric dispersions: Polymer, Plasticizer, Pore material, Pigment, Antiadherent Film formation mechanism of aqueous polymeric dispersions Coating methods: Pan coating, Roll coating, Fluidized bed coating, Compression coating