上商充通大睾 Mechanism of amphotericin B Shanghai Jiao Tong University Inhibiting synthesis of ergosterol(麦角甾 醇)，which forms a transmembrane channel.. Amphotericin B molecules can form pores in the host membrane as well as the fungal membrane.Shanghai Jiao Tong University Mechanism of amphotericin B Inhibiting synthesis of ergosterol（麦角甾 醇） , which forms a transmembrane channel. Amphotericin B molecules can form pores in the host membrane as well as the fungal membrane