Active site活性部位 Active site is the region that binds the substrate i and converts it into product 结合部位:负责与底物的结合,决定酶的专一性。 催化部位:负责催化底物键的断裂形成新键,决定酶的催 化能力。 Smal(1-2%)、 a three- dimensional entity实体 Cleft or crevice裂缝 on the surface of enzyme Bind by multiple weak forces Enzyme-substrate complex transition state complex过渡态复合物- productActive site活性部位 • Active site is the region that binds the substrate 底物 and converts it into product。 • 结合部位：负责与底物的结合，决定酶的专一性。 • 催化部位：负责催化底物键的断裂形成新键，决定酶的催 化能力。 • Small（1-2%）、a three-dimensional entity实体 • Cleft or crevice裂缝on the surface of enzyme • Bind by multiple weak forces • Enzyme-substrate complex • transition state complex过渡态复合物--→product