冷伤害的主要机理: 低温—→膜相变(液晶相→凝胶相) 凝胶相:膜收缩,透性增大,胞内内容物外渗 膜结合蛋白活性下降,代谢紊乱。 膜相变在一定温度范围内是可逆的。 Thermal transition from the gel phase( Lg to liquid crystalline phase(La) in a pure phosphatidylcholine bilayer (low panel) At low temperatures, motion of fatty acid chains is limited by Van der Waals forces. As the temperature is raised through the phase transition heat is absorbed and van Temperature der Waals forces are La disrupted to form a bilayer with melted fatty acid chains冷伤害的主要机理： 低温 —→ 膜相变（液晶相→ 凝胶相） 凝胶相：膜收缩，透性增大，胞内内容物外渗； 膜结合蛋白活性下降，代谢紊乱。 膜相变在一定温度范围内是可逆的。 • Thermal transition from the gel phase (Lß) to liquid crystalline phase (Lą ) in a pure phosphatidylcholine bilayer (low panel). • At low temperatures, motion of fatty acid chains is limited by Van der Waals forces. As the temperature is raised through the phase transition, heat is absorbed and Van der Waals forces are disrupted to form a bilayer with melted fatty acid chains