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R一C R-Ca :C Nuc: Nuc Nuc leaving group Therefore acid halides are very reactive toward nucleophilic attack,and the overall reaction is nucleophilic acyl substitution since the chloride is a good leaving group. Nomenclature Acid halides are named by taking the-ic acid suffix of the related carboxylic acid,replacing it with-yl,and adding the halide name. E.g. 0 Br CHgCH2-C-F H C-CHCH-C-CI propanoyl fluoride 3-bromobutanoyl chloride Ch21 Carboxylic acid Derivatives(landscape) Page 9Ch21 Carboxylic acid Derivatives(landscape) Page 9 Therefore acid halides are very reactive toward nucleophilic attack, and the overall reaction is nucleophilic acyl substitution since the chloride is a good leaving group. Nomenclature Acid halides are named by taking the -ic acid suffix of the related carboxylic acid, replacing it with -yl, and adding the halide name. E.g. CH3CH2 C O F CHCH2 C O Cl Br H3C propanoyl fluoride 3-bromobutanoyl chloride
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