The committed step in the do novo synthesis of purine nucleotides 0 O—PoCH2O、H Glutamine Glutamate-0-POCH20 NH HH 0K以+P 0-P-0-P-0 Amidophosphoribosyl transferase H HO OH 0-0 HO OH PRPP 5-Phosphoribosyl 1-amineThe committed step in the do novo synthesis of purine nucleotides