Penicillin production 10,000 NEW STRAIN 8 NEW MEDIUM REBALANCE- STRAIN 岳 PROGRAMMED FEEDING-NUTRIENT IMPROVEMENT NEW e STRAIN AERATION INOCULUM FEEDING 5000 MEDIUM- CULTURE EISOLATION MEDIUM 岳 REBALANCE INOCULUM PREPARATION NEW STRAIN AERATION AERATION MEDIUM 10004 °949 1951 1953 1955195719591961 1963 YEAR Figure 10.2 Influence of fermentation development studies on a typical antibiotic.(Courtesy of Bristol Laboratories.)Penicillin production