(2)prometaphase Nuclear membrane breaks apart(phosphorylation of lamins by MPF) ■Spindle appears Chromosome alignment(microtubules and motor proteins) Prophase Prometaphase Chromatids of Developing chromosomes spindle Aster The chromatin continues to The nuclear envelope breaks coil and supercoil,making down.Kinetochore microtub- the chromatin more and ules appear and interact with more compact.The chromo- the polar microtubules of the somes consist of identical, spindle,resulting in movement paired chromatids of the chromosomes This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more information