上游充通大学 Adverse drug effects Shanghai Jiao Tong University Mammalian and fungal membranes:similar in structure and composition-basis of cellular toxicity Severe and potentially lethal side effects: high fever,shaking chills,nausea, vomiting,.. long term use:nephrotoxicity(80%)Shanghai Jiao Tong University Adverse drug effects Mammalian and fungal membranes: similar in structure and composition—— basis of cellular toxicity Severe and potentially lethal side effects: high fever, shaking chills, nausea, vomiting, … long term use: nephrotoxicity(80%) …