Name Section: Question 2, continued In a typical muscle cell at rest the following concentrations are observed Metabolite Equilibrium Concentration mM) ATP 8.0 ADP 0.02 Pi 3.0 Creatine 3.0 Creatine Phosphate 26.0 c)Calculate the AG for creatine phosphate formation in these cells at 37C. Show all work. Under the above cellular conditions, is the synthesis of creatine phosphate spontaneous? d)Briefly explain why the AG you calculated is different from the ag given for the reaction nder standard conditions e)What would happen to the spontaneity of the reaction if the equilibrium [ADP] was raised by an order of magnitude, i.e. from 0.02mM to 0.2mM? What does this suggest about the importance of maintaining a high ratio of atp to adp in the cell? 7012Fall2003Name:___________________________________ Section:_____ 7.012 Fall 2003 Question 2, continued In a typical muscle cell at rest the following concentrations are observed: Metabolite Equilibrium Concentration (mM) ATP 8.0 ADP 0.02 Pi 3.0 Creatine 3.0 Creatine Phosphate 26.0 c) Calculate the ΔG for creatine phosphate formation in these cells at 37°C. Show all work. Under the above cellular conditions, is the synthesis of creatine phosphate spontaneous? d) Briefly explain why the ΔG you calculated is different from the ΔG° given for the reaction under standard conditions. e) What would happen to the spontaneity of the reaction if the equilibrium [ADP] was raised by an order of magnitude, i.e. from 0.02mM to 0.2mM? What does this suggest about the importance of maintaining a high ratio of ATP to ADP in the cell?