New lon Channel Players Voltage-gated Ca2+ channel >in presynaptic nerve terminal >mediates neurotransmitter release Nicotinic Acetylcholine Receptor Channel >in muscle neuromuscular junction(postsynaptic membrane, or end plate) >mediates electrical transmission from nerve to muscle Motor ne uscle fiber nucleus Myofibril of muscle fiber Motor end plate8 New Ion Channel Players ➢Voltage-gated Ca2+ channel ➢in presynaptic nerve terminal ➢mediates neurotransmitter release ➢Nicotinic Acetylcholine Receptor Channel ➢in muscle neuromuscular junction (postsynaptic membrane, or end plate) ➢mediates electrical transmission from nerve to muscle