Extracorpuscular Hemolysis Immune g All require antigen-antibody reactions Types of reactions dependent on RR Class of antibody cRNumber spacing of antigenic sites on cell aVAilability of complement cR Environmental Temperature c& Functional status of reticuloendothelial system ☆ Manifestations c&Intravascular hemolysis eXTravascular hemolysisExtracorpuscular Hemolysis Immune ❖ All require antigen-antibody reactions ❖ Types of reactions dependent on: Class of Antibody Number & Spacing of antigenic sites on cell Availability of complement Environmental Temperature Functional status of reticuloendothelial system ❖ Manifestations Intravascular hemolysis Extravascular hemolysis