Pathogenesis 5. Brain infected 6 Virus travels fom brain via nerves to other tissues such as eye, kidneys, salivary glands 4. Virus replicates in dorsal root ganghion 3 Virus infects nerve in and travels up spinal cord to brain peripheral nervous system Moves by retrograde 1. Virus enters transport via anmal bite 2. Virus replicates in muscle at site of bitePathogenesis