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21.5 Steroid receptors have DNA-bind ing and severalindependent domains transcriptional-activation (domains vary from 94-42%) N-terminal regions Hormone-binding regions have <15 identities and dimerization (needed to activ ate (vary from 57-15%) Figure 21. 8 Receptors transcription Glucocorticoid for many steroid and thyroid hormones have 4 57 Mineralocorticoid 90 55 Progesterone a similar organization with an individual n 50 Androgen terminal region, 52 30Estrogen conserved dna 47 17 Trio dothyronine binding region, and a 42<15 Vitamin D C-terminal hormone binding region L 45 15Retinoic acid 40 15 9-cis Retinoic acid 请莘大Figure 21.8 Receptors for many steroid and thyroid hormones have a similar organization, with an individual N￾terminal region, conserved DNA￾binding region, and a C-terminal hormone￾binding region. 21.5 Steroid receptors have several independent domains
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