Solved Problem 1 Predict the major product(s)of bromination of p-chloroacetanilide. C-CH Solution The amide group(-NHCOCH3)is a strong activating and directing group because the nitrogen atom with its nonbonding pair ofelectrons is bonded to the aromatic ring.The amide group is a stronger director than the chlorine atom,and substitution occurs mostly at the positions ortho to the amide.Like an alkoxyl group,the amide is a particularly strong activating group,and the reaction gives some of the dibrominated product. H O H :N-C-CH3 :N- CH N C一CH Br2 H2O CI p-chloroacetanilide Chapter 17 9Chapter 17 9 Predict the major product(s) of bromination of p-chloroacetanilide. The amide group (–NHCOCH3 ) is a strong activating and directing group because the nitrogen atom with its nonbonding pair of electrons is bonded to the aromatic ring. The amide group is a stronger director than the chlorine atom, and substitution occurs mostly at the positions ortho to the amide. Like an alkoxyl group, the amide is a particularly strong activating group, and the reaction gives some of the dibrominated product. Solved Problem 1 Solution