History(cont'd) 1990 NIH and DOE publish a 5-year plan. Goals include a complete genetic map, a physical map with markers every 100 kb, and sequencing of an aggregate of 20 Mb of DNA in model organisms by NIH and DOE restart the clock, declaring I October the official beginning of the HGP Cost per base David Lipman, Eugene Myers(CU CS Department! ) and colleagues at the National Center for Biotechnology Information(NCBD publish the BLAST algorithm for aligning sequences 1991 NIH biologist J. Craig Venter announces a strategy to find expressed genes, using ESTS (Science ) A fight erupts at a congressional hearing I month later, when Venter reveals is filing patent applications on thousands of these partial genesHistory (cont’d) – 1990 NIH and DOE publish a 5-year plan. Goals include a complete genetic map, a physical map with markers every 100 kb, and sequencing of an aggregate of 20 Mb of DNA in model organisms by 2005 NIH and DOE restart the clock, declaring 1 October the official beginning of the HGP. Cost per base ~$0.75 David Lipman, Eugene Myers (CU CS Department!), and colleagues at the National Center for Biotechnology Information (NCBI) publish the BLAST algorithm for aligning sequences – 1991 NIH biologist J. Craig Venter announces a strategy to find expressed genes, using ESTs (Science ). A fight erupts at a congressional hearing 1 month later, when Venter reveals that NIH is filing patent applications on thousands of these partial genes