Regioselectivity Markovnikov's Rule:The addition of a proton to the double bond of an alkene results in a product with the acidic proton bonded to the carbon atom that already holds the greater number of hydrogens. Markovnikov's Rule (extended):In an electrophilic addition to the alkene,the electrophile adds in such a way that it generates the most stable intermediate Chapter 8 7 Chapter 8 7 Regioselectivity • Markovnikov’s Rule: The addition of a proton to the double bond of an alkene results in a product with the acidic proton bonded to the carbon atom that already holds the greater number of hydrogens. • Markovnikov’s Rule (extended): In an electrophilic addition to the alkene, the electrophile adds in such a way that it generates the most stable intermediate