Properties of HHV (cont) Replication: Nuclear. Assembly: Nuclear. Common Antigens: None! Set up latent or persistent infection following primary infection Reactivation are more likely to take place during periods of immunosuppression Both primary infection and reactivation are likely to be more serious in immunocompromised patients.Properties of HHV (cont.)  Replication: Nuclear.  Assembly: Nuclear.  Common Antigens: None!  Set up latent or persistent infection following primary infection  Reactivation are more likely to take place during periods of immunosuppression  Both primary infection and reactivation are likely to be more serious in immunocompromised patients