Plasmid EcoRl EcoRly ⊙ AATICR DNA to be inserted CITAA.G CTTAA EcoRI EcoRl EcoRI DNA is cut with EcoRl at arrows. CTTAA AATTC EcoRL Sticky ends DNA recombination+ DNA ligase MOUIE A Mismatch Recombinant Mismatch DNA Inserting a DNA Sample into a Plasmid