Is Toxin Important in Infection? Questions to ask: Is virulence quantitatively correlated with toxin production? Does the purified toxin produce damage Can a specific antibody(antitoxin) prevent or alleviate the manifestations of the disease? If toxin production is impaired by a mutation is the disease process affected? BIOL 533 Lecture 9BIOL 533 5 Lecture 9 Is Toxin Important in Infection? • Questions to ask: – Is virulence quantitatively correlated with toxin production? – Does the purified toxin produce damage? – Can a specific antibody (antitoxin) prevent or alleviate the manifestations of the disease? – If toxin production is impaired by a mutation, is the disease process affected?