1.Overview and concepts Single-gene disorders:genetic disorders caused by a single mutant gene. Locus:a segment of DNA occupying a particular position or location on a chromosome. Alleles:Alternative variants of a gene. wild type allele/common allele; mutant allele/variant allele. Mutation:indicate a new genetic change or merely a disease-causing mutant allele. This document is produced by trial version of Print2Flash.Visit www.print2flash.com for more informationThis document is produced by trial version of Print2Flash. Visit www.print2flash.com for more information