The phosphorylase b kinases in muscle and liver are controlled by two different hormones, epinephrine(肾上腺素)and g! ucagon(胰增血糖素) respectively.D High level of amp binds to and activates the b form of the muscle isozyme which is blocked by a high level of aTp High level of glucose binds to the a form of the liver isozyme exposing the phosphorylated ser residues to the action of phosphorylase a phosphatase and converting it to the less active b form◆ The phosphorylase b kinases in muscle and liver are controlled by two different hormones, epinephrine (肾上腺素) and glucagon(胰增血糖素) respectively. • ◆ High level of AMP binds to and activates the b form of the muscle isozyme, which is blocked by a high level of ATP. • ◆ High level of glucose binds to the a form of the liver isozyme, exposing the phosphorylated Ser residues to the action of phosphorylase a phosphatase and converting it to the less active b form