Reactions of Amines -Major product is the less highly substituted alkene Base abstracts hydrogen from least hindered position due to the sterically bulky trialkylamine leaving group H3C CH3 -OH H N-CH3 CH3CH2 H H HH H Less hindered; more accessible More hindered; less accessible (1-Methylbutyl)trimethylammonium hydroxide CH3CH2CH2CH=CH2+ CH3CH2CH=CHCH3 Pent-1-ene Pent-2-ene (94%) (6%) Len时.对 ▪ Major product is the less highly substituted alkene ▪ Base abstracts hydrogen from least hindered position due to the sterically bulky trialkylamine leaving group Reactions of Amines