Mucin 4 v This gene encodes an integral membrane glycoprotein found on the cell surface. although secreted isoforms may exist wth EGF-lke doman The major constituents of mucus EGF-lke the viscous secretion that covers MUCA epithelial surfaces such as those ERBB2 Knaso MUCT in the trachea. colon and cervix MUC-4 has been found to play various roles in the progression of cancer, particularly due to its MAPK signaling signaling and anti-adhesive properties which contribute to tumor development and Nudeus( TCFAE metastasis It should be noted that MUC-4 is not found in the gall bladder, Nature Reviews I Cancer pancreas, or liver except in abnormal conditions such as cancer This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist  The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix  MUC -4 has been found to play various roles in the progression of cancer, particularly due to its signaling and anti -adhesive properties which contribute to tumor development and metastasis  It should be noted that MUC -4 is not found in the gall bladder, pancreas, or liver except in abnormal conditions such as cancer 17 Mucin 4