X-chromosome linked diseases Androgen insensivity syndrome The gene encoding the androgen receptor is encoded on the x-chromosome This individual is a XY karyotype with a mutation in the androgen receptor He/she has undescended testes which produce testosterone and no uterus or oviducts Otherwise she is a phenotypical womanAndrogen insensivity syndrome The gene encoding the androgen receptor is encoded on the X-Chromosome This individual is a XY karyotype with a mutation in the androgen receptor He/She has undescended testes, which produce testosterone and no uterus or oviducts. Otherwise she is a phenotypical woman X-chromosome linked diseases