Williamson Synthesis ·Alkoxide ion+1°alkyl bromide(or tosylate) 、Example: CH3 CH3 CH-O-H+K→CH,-O-K CH3 CH3 CH3 CH3-O- +CHCH2一C Br →CH3O-CH2CH2CH3+Br CH3 H CH => Chapter 14 13 Chapter 14 13 Williamson Synthesis • Alkoxide ion + 1 alkyl bromide (or tosylate) • Example: CH3 O H CH3 CH3 + K CH3 O CH3 CH3 _ K + CH3 O CH3 CH3 _ + CH3CH2 C H H Br CH3 O CH3 CH3 CH2CH2CH3 + Br _ =>