The structure changes of cardiovascular system will be responsible for the functional changes that disturb whole and or local blood circulation The disorders of cardiovascular system affect the human health and life and are a leading cause of death in the world The valve of normal heart◼ The structure changes of cardiovascular system will be responsible for the functional changes that disturb whole and/or local blood circulation. The disorders of cardiovascular system affect the human health and life and are a leading cause of death in the world. The valve of normal heart