Medical Genetics Natural killer cell deficiency Severe herpes viral infection Idiopathic CD4 lymphocytopenia Often asymptomatic Combined t- and B-cell deficiencies Severe combined immunodeficiency (AR or XL) Adenosine deaminase deficiency (AR Skeletal abnormalities Reticular dysgenesis Pancytopenia Bare lymphocyte syndrome Absence of HLa Ataxia-telangiectasia (AR) Dermatitis, neurologic deterioration Wiskott-Aldrich syndrome (XL) Eczema, thrombocytopenia Short-limbed dwarfism Cartilage-hair hypoplasia, severe varicella XL lymphoproliferative syndrome Severe Epstein- Barr virus infection Phagocytic disorders Defects of cell movement Hyperimmunoglobulinemia E syndrome Staphylococcal infections, eczema, der. mattis Leukocyte adhesion defect type 1 (AR) Prolonged attachment of umbilical cord. leukocytosis, periodontitis Defects of microbicidal activity Chronic granulomatous disease (XL or AR) Lymphadenopathy Neutrophil G6PD deficiency Myeloperoxidase deficiency (AR) Chediak-Higashi syndrome(AR) Oculocutaneous albinism, giant granules of neutrophilsMedical Genetics